While addiction has long proliferated as a personality disorder, in recent years it has begun to be recognized as a brain disease. Cigarette, which is made by wrapping tobacco leaves in a thin paper, is a substance that is consumed by inhaling the smoke after burning. The active ingredient is a dark liquid called nicotine. Nicotine increases the release of epinephrine, norepinephrine and serotonin in the brain. Nowadays, addiction disease, which is extremely important for individuals and public health, is becoming more and more common and affects people of all ages. As research shows how serious cigarette addiction is, it is a situation that should not be ignored. According to research conducted by the World Health Organization in 2021, 1.5 billion people worldwide smoke. Smokers are more intolerant to exercise and finish exercise in a shorter time. Non-smokers can maintain a maximal level of exercise for longer than smokers.  in various studies, it is estimated that different types of exercises and physical activities have a reducing effect on smoking addiction and the physiological factors that cause the feeling of smoking, and that more detailed explanations will be provided on exercise and smoking addiction with new research in the future.